The maturation of infant and toddler visual cortex neural activity and associations with fine motor performance
Our understanding of how visual cortex neural processes mature during infancy and toddlerhood is limited. Using magnetoencephalography (MEG), the present study investigated the development of visual evoked responses (VERs) in cross-sectional and longitudinal samples of infants and toddlers 2 months...
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Elsevier
2025-01-01
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| Series: | Developmental Cognitive Neuroscience |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1878929324001622 |
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| author | Katharina Otten J. Christopher Edgar Heather L. Green Kylie Mol Marybeth McNamee Emily S. Kuschner Mina Kim Song Liu Hao Huang Marisa Nordt Kerstin Konrad Yuhan Chen |
| author_facet | Katharina Otten J. Christopher Edgar Heather L. Green Kylie Mol Marybeth McNamee Emily S. Kuschner Mina Kim Song Liu Hao Huang Marisa Nordt Kerstin Konrad Yuhan Chen |
| author_sort | Katharina Otten |
| collection | DOAJ |
| description | Our understanding of how visual cortex neural processes mature during infancy and toddlerhood is limited. Using magnetoencephalography (MEG), the present study investigated the development of visual evoked responses (VERs) in cross-sectional and longitudinal samples of infants and toddlers 2 months to 3 years. Brain space analyses focused on N1m and P1m latency, as well as N1m-to-P1m amplitude. Associations between VER measures and developmental quotient (DQ) scores in the cognitive/visual and fine motor domains were also examined. Results showed a nonlinear decrease in N1m and P1m latency as a function of age, characterized by rapid changes followed by slower progression, with the N1m latency plateauing at 6–7 months and the P1m latency plateauing at 8–9 months. The N1m-to-P1m amplitude also exhibited a non-linear decrease, with strong responses observed in younger infants (∼2–3 months) and then a gradual decline. Associations between N1m and P1m latency and fine motor DQ scores were observed, suggesting that infants with faster visual processing may be better equipped to perform fine motor tasks. The present findings advance our understanding of the maturation of the infant visual system and highlight the relationship between the maturation of the visual system and fine motor skills. |
| format | Article |
| id | doaj-art-fa283c33e1364339ada997d8929bed98 |
| institution | Kabale University |
| issn | 1878-9293 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Developmental Cognitive Neuroscience |
| spelling | doaj-art-fa283c33e1364339ada997d8929bed982025-01-22T05:41:20ZengElsevierDevelopmental Cognitive Neuroscience1878-92932025-01-0171101501The maturation of infant and toddler visual cortex neural activity and associations with fine motor performanceKatharina Otten0J. Christopher Edgar1Heather L. Green2Kylie Mol3Marybeth McNamee4Emily S. Kuschner5Mina Kim6Song Liu7Hao Huang8Marisa Nordt9Kerstin Konrad10Yuhan Chen11Child Neuropsychology Section, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Faculty of Medicine, RWTH Aachen University, Aachen 52074, Germany; Department of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, RWTH Aachen University, Aachen, Germany; Correspondence to: Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy Faculty of Medicine, RWTH Aachen University, Neuenhofer Weg 21, Aachen 52074, Germany.Lurie Family Foundations MEG Imaging Center, Dept. of Radiology, Children’s Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USALurie Family Foundations MEG Imaging Center, Dept. of Radiology, Children’s Hospital of Philadelphia, Philadelphia, PA 19104, USALurie Family Foundations MEG Imaging Center, Dept. of Radiology, Children’s Hospital of Philadelphia, Philadelphia, PA 19104, USALurie Family Foundations MEG Imaging Center, Dept. of Radiology, Children’s Hospital of Philadelphia, Philadelphia, PA 19104, USADepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USALurie Family Foundations MEG Imaging Center, Dept. of Radiology, Children’s Hospital of Philadelphia, Philadelphia, PA 19104, USALurie Family Foundations MEG Imaging Center, Dept. of Radiology, Children’s Hospital of Philadelphia, Philadelphia, PA 19104, USALurie Family Foundations MEG Imaging Center, Dept. of Radiology, Children’s Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USAChild Neuropsychology Section, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Faculty of Medicine, RWTH Aachen University, Aachen 52074, Germany; JARA-Brain Institute II, Molecular Neuroscience and Neuroimaging (INM-11), RWTH Aachen & Research Centre Jülich, Jülich 52428, GermanyChild Neuropsychology Section, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Faculty of Medicine, RWTH Aachen University, Aachen 52074, Germany; JARA-Brain Institute II, Molecular Neuroscience and Neuroimaging (INM-11), RWTH Aachen & Research Centre Jülich, Jülich 52428, GermanyLurie Family Foundations MEG Imaging Center, Dept. of Radiology, Children’s Hospital of Philadelphia, Philadelphia, PA 19104, USAOur understanding of how visual cortex neural processes mature during infancy and toddlerhood is limited. Using magnetoencephalography (MEG), the present study investigated the development of visual evoked responses (VERs) in cross-sectional and longitudinal samples of infants and toddlers 2 months to 3 years. Brain space analyses focused on N1m and P1m latency, as well as N1m-to-P1m amplitude. Associations between VER measures and developmental quotient (DQ) scores in the cognitive/visual and fine motor domains were also examined. Results showed a nonlinear decrease in N1m and P1m latency as a function of age, characterized by rapid changes followed by slower progression, with the N1m latency plateauing at 6–7 months and the P1m latency plateauing at 8–9 months. The N1m-to-P1m amplitude also exhibited a non-linear decrease, with strong responses observed in younger infants (∼2–3 months) and then a gradual decline. Associations between N1m and P1m latency and fine motor DQ scores were observed, suggesting that infants with faster visual processing may be better equipped to perform fine motor tasks. The present findings advance our understanding of the maturation of the infant visual system and highlight the relationship between the maturation of the visual system and fine motor skills.http://www.sciencedirect.com/science/article/pii/S1878929324001622InfantsMagnetoencephalography (MEG)Visual evoked responses (VER)MaturationFine motorDevelopmental trajectory |
| spellingShingle | Katharina Otten J. Christopher Edgar Heather L. Green Kylie Mol Marybeth McNamee Emily S. Kuschner Mina Kim Song Liu Hao Huang Marisa Nordt Kerstin Konrad Yuhan Chen The maturation of infant and toddler visual cortex neural activity and associations with fine motor performance Developmental Cognitive Neuroscience Infants Magnetoencephalography (MEG) Visual evoked responses (VER) Maturation Fine motor Developmental trajectory |
| title | The maturation of infant and toddler visual cortex neural activity and associations with fine motor performance |
| title_full | The maturation of infant and toddler visual cortex neural activity and associations with fine motor performance |
| title_fullStr | The maturation of infant and toddler visual cortex neural activity and associations with fine motor performance |
| title_full_unstemmed | The maturation of infant and toddler visual cortex neural activity and associations with fine motor performance |
| title_short | The maturation of infant and toddler visual cortex neural activity and associations with fine motor performance |
| title_sort | maturation of infant and toddler visual cortex neural activity and associations with fine motor performance |
| topic | Infants Magnetoencephalography (MEG) Visual evoked responses (VER) Maturation Fine motor Developmental trajectory |
| url | http://www.sciencedirect.com/science/article/pii/S1878929324001622 |
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