Acute myeloid leukemia-derived bone marrow mesenchymal cells exhibit improved support for leukemic cell proliferation

Acute myeloid leukemia-derived bone marrow mesenchymal cells exhibit improved support for leukemic cell proliferation

Introduction: The bone marrow (BM) microenvironment plays a significant role in acute myeloid leukemia (AML) genesis and there is evidence that BM mesenchymal stromal cells (BMMSCs) can support leukemia progenitor cell proliferation and survival and provide resistance to cytotoxic therapies. Hypothe...

Full description

Saved in:
Bibliographic Details
Main Authors: Mariane Cristina do Nascimento, Diego A. Pereira-Martins, João Agostinho Machado-Neto, Eduardo M. Rego
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Hematology, Transfusion and Cell Therapy
Subjects:
Bone marrow microenvironment
Acute myeloid leukemia
Cell proliferation
Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2531137923026020
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S2531137923026020

Similar Items