Combination of low-intensity pulsed ultrasound irradiating immune organs with immune checkpoint blockade augments systemic anti-tumor immunity on low tumor burden 4T-1 breast cancer

Combination of low-intensity pulsed ultrasound irradiating immune organs with immune checkpoint blockade augments systemic anti-tumor immunity on low tumor burden 4T-1 breast cancer

Abstract Background Despite achieving complete remission (CR) through surgery, chemoradiotherapy, targeted therapy, and other treatment modalities, breast cancer, particularly triple-negative breast cancer (TNBC) remains at a high risk of recurrence and metastasis. Enhancing anti-tumor immunity to e...

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Bibliographic Details
Main Authors: Jixi Li, Linqing Wen, Yujun Guo, Dan Yao, Bihang Sun, Hai Mou, Nianzhi Chen, Kun Zhou, Yan Wang, Wenzhi Chen
Format: Article
Language:English
Published: Springer 2025-08-01
Series:Cancer Immunology, Immunotherapy
Subjects:
Low-intensity pulsed ultrasound
Triple-negative breast cancer
4T-1 breast cancer
Low tumor burden
Immune checkpoint blockade
Anti-tumor immunity
Online Access:https://doi.org/10.1007/s00262-025-04137-6
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https://doi.org/10.1007/s00262-025-04137-6

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