Design and Synthesis of Novel 6-(Substituted phenyl)-[1,3]dioxolo[4′,5′:4,5]benzo[1,2-<i>d</i>]thiazole Compounds as Tyrosinase Inhibitors: In Vitro and In Vivo Insights

Design and Synthesis of Novel 6-(Substituted phenyl)-[1,3]dioxolo[4′,5′:4,5]benzo[1,2-<i>d</i>]thiazole Compounds as Tyrosinase Inhibitors: In Vitro and In Vivo Insights

The 2,4-dihydroxyphenyl group is commonly present in the chemical structures of potent tyrosinase inhibitors. Based on this observation, a series of 6-(substituted phenyl)-[1,3]dioxolo[4′,5′:4,5]benzo[1,2-<i data-eusoft-scrollable-element="1">d</i>]thiazole compounds <b data...

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Bibliographic Details
Main Authors: Hyeon Seo Park, Hee Jin Jung, Hye Soo Park, Hye Jin Kim, Sang Gyun Noh, Yujin Park, Pusoon Chun, Hae Young Chung, Hyung Ryong Moon
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Molecules
Subjects:
melanin
tyrosinase
2,4-dihydroxyphenyl
zebrafish embryos
depigmentation
Online Access:https://www.mdpi.com/1420-3049/30/7/1535
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