The Role of A20 in Cancer: Friend or Foe?

A20 is a ubiquitin-editing enzyme that has emerged as a key regulator of inflammatory signaling with paradoxical roles in cancer. Acting as both an oncogene and a tumor suppressor gene depending on the cellular context, A20 modulates important cell pathways, such as NF-κB signaling and autophagy. In...

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Bibliographic Details
Main Authors: Jinju Lee, Heesun Cheong
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/14/7/544
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