Synthesis and Evaluation of Ethyl 2,4-dioxo-4-arylbutanoate Derivatives as Src Kinase Inhibitors

In this work, different ethyl 2,4-dioxo-4-arylbutanoate derivatives were prepared and evaluated for their Src Kinase inhibitory activity. For this purpose, the appropriate substituted acetophenone derivatives reacted with diethyl oxalate in the presence of sodium ethoxide in dried ethanol to give th...

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Bibliographic Details
Main Authors: T. Akbarzadeh, A. Rafinejad, A. Fallah-Tafti, R. Tiwari, A. Nasrolahi Shirazi, D. Mandal, K. Parang, A. Foroumadi
Format: Article
Language:English
Published: University of Tehran 2015-12-01
Series:Journal of Sciences, Islamic Republic of Iran
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Online Access:https://jsciences.ut.ac.ir/article_55999_438a64a1dae5907a2b6f80bb64301ead.pdf
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