Clinical Application of Partial Splenic Embolization

Partial splenic embolization (PSE) is one of the intra-arterial therapeutic approaches of diseases. With the development of interventional radiology, the applications of PSE in clinical practice are greatly extended, while various materials are developed for embolization use. Common indications of P...

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Main Authors: Yong-Song Guan, Ying Hu
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2014/961345
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author Yong-Song Guan
Ying Hu
author_facet Yong-Song Guan
Ying Hu
author_sort Yong-Song Guan
collection DOAJ
description Partial splenic embolization (PSE) is one of the intra-arterial therapeutic approaches of diseases. With the development of interventional radiology, the applications of PSE in clinical practice are greatly extended, while various materials are developed for embolization use. Common indications of PSE include hypersplenism with portal hypertension, hereditary spherocytosis, thalassemia, autoimmune hemolytic anemia, splenic trauma, idiopathic thrombocytopenic purpura, splenic hemangioma, and liver cancer. It is also performed to exclude splenic artery aneurysms from the parent vessel lumen and prevent aneurysm rupture, to treat splenic artery steal syndrome and improve liver perfusion in liver transplant recipients, and to administer targeted treatment to areas of neoplastic disease in the splenic parenchyma. Indicators of the therapeutic effect evaluation of PSE comprise blood routine test, changes in hemodynamics and in splenic volume. Major complications of PSE include the pulmonary complications, severe infection, damages of renal and liver function, and portal vein thrombosis. The limitations of PSE exist mainly in the difficulties in selecting the arteries to embolize and in evaluating the embolized volume.
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spelling doaj-art-f9e65f20b164400bb6de42b618c4e7212025-02-03T01:27:34ZengWileyThe Scientific World Journal2356-61401537-744X2014-01-01201410.1155/2014/961345961345Clinical Application of Partial Splenic EmbolizationYong-Song Guan0Ying Hu1Department of Oncology, West China Hospital, Sichuan University, Chengdu 610041, ChinaDepartment of Oncology, West China Hospital, Sichuan University, Chengdu 610041, ChinaPartial splenic embolization (PSE) is one of the intra-arterial therapeutic approaches of diseases. With the development of interventional radiology, the applications of PSE in clinical practice are greatly extended, while various materials are developed for embolization use. Common indications of PSE include hypersplenism with portal hypertension, hereditary spherocytosis, thalassemia, autoimmune hemolytic anemia, splenic trauma, idiopathic thrombocytopenic purpura, splenic hemangioma, and liver cancer. It is also performed to exclude splenic artery aneurysms from the parent vessel lumen and prevent aneurysm rupture, to treat splenic artery steal syndrome and improve liver perfusion in liver transplant recipients, and to administer targeted treatment to areas of neoplastic disease in the splenic parenchyma. Indicators of the therapeutic effect evaluation of PSE comprise blood routine test, changes in hemodynamics and in splenic volume. Major complications of PSE include the pulmonary complications, severe infection, damages of renal and liver function, and portal vein thrombosis. The limitations of PSE exist mainly in the difficulties in selecting the arteries to embolize and in evaluating the embolized volume.http://dx.doi.org/10.1155/2014/961345
spellingShingle Yong-Song Guan
Ying Hu
Clinical Application of Partial Splenic Embolization
The Scientific World Journal
title Clinical Application of Partial Splenic Embolization
title_full Clinical Application of Partial Splenic Embolization
title_fullStr Clinical Application of Partial Splenic Embolization
title_full_unstemmed Clinical Application of Partial Splenic Embolization
title_short Clinical Application of Partial Splenic Embolization
title_sort clinical application of partial splenic embolization
url http://dx.doi.org/10.1155/2014/961345
work_keys_str_mv AT yongsongguan clinicalapplicationofpartialsplenicembolization
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