Humanized mouse models in MDS

Abstract Myelodysplastic syndromes (MDS) are heterogeneous hematopoietic stem cell disorders defined by ineffective hematopoiesis, multilineage dysplasia, and risk of progression to acute myeloid leukemia. Improvements have been made to identify recurrent genetic mutations and their functional roles...

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Main Authors: Raluca Munteanu, Diana Gulei, Cristian Silviu Moldovan, Emanuele Azzoni, Laura Belver, Richard Feder, Simina Pirv, Anca Dana Buzoianu, Hermann Einsele, Moshe Mittelman, Gabriel Ghiaur, Robert Hasserjian, Ciprian Tomuleasa
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07861-0
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