QSAR modeling of antimalarial activity of urea derivatives using genetic algorithm–multiple linear regressions

A quantitative structure–activity relationship (QSAR) was performed to analyze antimalarial activities of 68 urea derivatives using multiple linear regressions (MLR). QSAR analyses were performed on the available 68 IC50 oral data based on theoretical molecular descriptors. A suitable set of molecul...

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Bibliographic Details
Main Authors: Abolghasem Beheshti, Eslam Pourbasheer, Mehdi Nekoei, Saadat Vahdani
Format: Article
Language:English
Published: Springer 2016-05-01
Series:Journal of Saudi Chemical Society
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610312001287
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