A spatio-temporal brain miRNA expression atlas identifies sex-independent age-related microglial driven miR-155-5p increase

A spatio-temporal brain miRNA expression atlas identifies sex-independent age-related microglial driven miR-155-5p increase

Abstract An in-depth understanding of the molecular processes composing aging is crucial to develop therapeutic approaches that decrease aging as a key risk factor for cognitive decline. Herein, we present a spatio-temporal brain atlas (15 different regions) of microRNA expression across the mouse l...

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Main Authors: Annika Engel, Viktoria Wagner, Oliver Hahn, Aulden G. Foltz, Micaiah Atkins, Amila Beganovic, Ian H. Guldner, Nannan Lu, Aryaman Saksena, Ulrike Fischer, Nicole Ludwig, Eckart Meese, Tony Wyss-Coray, Andreas Keller
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59860-6
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https://doi.org/10.1038/s41467-025-59860-6

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