Evaluating the effects of seed oils on lipid profile, inflammatory and oxidative markers, and glycemic control of diabetic and dyslipidemic patients: a systematic review of clinical studies
Diabetes mellitus and dyslipidemia are significant health concerns that elevate the risk of cardiovascular disease and other metabolic disorders, necessitating effective management strategies. Recent research has highlighted the potential role of dietary fats, particularly seed oils, in influencing...
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Frontiers Media S.A.
2025-02-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2025.1502815/full |
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| author | Lucas Fornari Laurindo Lucas Fornari Laurindo Lucas Fornari Laurindo Lívia Fornari Laurindo Victória Dogani Rodrigues Jéssica da Silva Camarinha Oliveira Beatriz Leme Boaro Adriano Cressoni Araújo Adriano Cressoni Araújo Elen Landgraf Guiguer Elen Landgraf Guiguer Elen Landgraf Guiguer Claudia Rucco Penteado Detregiachi Claudia Rucco Penteado Detregiachi Virgínia Maria Cavallari Strozze Catharin Virgínia Maria Cavallari Strozze Catharin Eduardo Federighi Baisi Chagas Eduardo Federighi Baisi Chagas Vitor Cavallari Strozze Catharin Vitor Cavallari Strozze Catharin Rosa Direito Sandra Maria Barbalho Sandra Maria Barbalho Sandra Maria Barbalho Sandra Maria Barbalho |
| author_facet | Lucas Fornari Laurindo Lucas Fornari Laurindo Lucas Fornari Laurindo Lívia Fornari Laurindo Victória Dogani Rodrigues Jéssica da Silva Camarinha Oliveira Beatriz Leme Boaro Adriano Cressoni Araújo Adriano Cressoni Araújo Elen Landgraf Guiguer Elen Landgraf Guiguer Elen Landgraf Guiguer Claudia Rucco Penteado Detregiachi Claudia Rucco Penteado Detregiachi Virgínia Maria Cavallari Strozze Catharin Virgínia Maria Cavallari Strozze Catharin Eduardo Federighi Baisi Chagas Eduardo Federighi Baisi Chagas Vitor Cavallari Strozze Catharin Vitor Cavallari Strozze Catharin Rosa Direito Sandra Maria Barbalho Sandra Maria Barbalho Sandra Maria Barbalho Sandra Maria Barbalho |
| author_sort | Lucas Fornari Laurindo |
| collection | DOAJ |
| description | Diabetes mellitus and dyslipidemia are significant health concerns that elevate the risk of cardiovascular disease and other metabolic disorders, necessitating effective management strategies. Recent research has highlighted the potential role of dietary fats, particularly seed oils, in influencing health outcomes in these conditions. This systematic review evaluates the impact of seed oils on lipid profiles, inflammatory and oxidative markers, and glycemic control in patients with diabetes and dyslipidemia. A comprehensive search across databases, including PubMed, Scopus, Web of Science, Cochrane Library, and Google Scholar, identified studies focusing on the effects of seed oils. The studies include randomized controlled, parallel-design, double-blind, placebo-controlled, and open-label studies published in English. The quality of the studies was assessed through a detailed review process, and data were extracted to evaluate the effects of seed oils on key metabolic markers. The review included 11 studies demonstrating that seed oils derived from canola, flaxseed, and sesame seeds can positively influence lipid profiles and glycemic control while potentially modulating oxidative stress markers. The findings suggest that seed oils may benefit in managing diabetes and dyslipidemia, although the results are sometimes inconsistent. This review provides valuable insights for dietary recommendations and therapeutic strategies, highlighting the need for further research to clarify the role of seed oils in metabolic health. |
| format | Article |
| id | doaj-art-f9c44ea65eb54c259b8b14cc57df919c |
| institution | Kabale University |
| issn | 2296-861X |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj-art-f9c44ea65eb54c259b8b14cc57df919c2025-02-07T15:59:06ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2025-02-011210.3389/fnut.2025.15028151502815Evaluating the effects of seed oils on lipid profile, inflammatory and oxidative markers, and glycemic control of diabetic and dyslipidemic patients: a systematic review of clinical studiesLucas Fornari Laurindo0Lucas Fornari Laurindo1Lucas Fornari Laurindo2Lívia Fornari Laurindo3Victória Dogani Rodrigues4Jéssica da Silva Camarinha Oliveira5Beatriz Leme Boaro6Adriano Cressoni Araújo7Adriano Cressoni Araújo8Elen Landgraf Guiguer9Elen Landgraf Guiguer10Elen Landgraf Guiguer11Claudia Rucco Penteado Detregiachi12Claudia Rucco Penteado Detregiachi13Virgínia Maria Cavallari Strozze Catharin14Virgínia Maria Cavallari Strozze Catharin15Eduardo Federighi Baisi Chagas16Eduardo Federighi Baisi Chagas17Vitor Cavallari Strozze Catharin18Vitor Cavallari Strozze Catharin19Rosa Direito20Sandra Maria Barbalho21Sandra Maria Barbalho22Sandra Maria Barbalho23Sandra Maria Barbalho24Department of Biochemistry and Pharmacology, School of Medicine, Faculdade de Medicina de Marília (FAMEMA), Marília, São Paulo, BrazilDepartment of Administration, Associate Degree in Hospital Management, Universidade de Marília (UNIMAR), Marília, São Paulo, BrazilDepartment of Biochemistry and Pharmacology, School of Medicine, Universidade de Marília (UNIMAR), Marília, São Paulo, BrazilDepartment of Biochemistry and Pharmacology, School of Medicine, Faculdade de Medicina de São José do Rio Preto (FAMERP), São José do Rio Preto, São Paulo, BrazilDepartment of Biochemistry and Pharmacology, School of Medicine, Faculdade de Medicina de Marília (FAMEMA), Marília, São Paulo, BrazilDepartment of Biochemistry and Pharmacology, School of Medicine, Faculdade de Medicina de Marília (FAMEMA), Marília, São Paulo, BrazilDepartment of Biochemistry and Pharmacology, School of Medicine, Faculdade de Medicina de Marília (FAMEMA), Marília, São Paulo, BrazilDepartment of Biochemistry and Pharmacology, School of Medicine, Universidade de Marília (UNIMAR), Marília, São Paulo, BrazilPostgraduate Program in Structural and Functional Interactions in Rehabilitation, School of Medicine, Universidade de Marília (UNIMAR), Marília, São Paulo, BrazilDepartment of Biochemistry and Pharmacology, School of Medicine, Universidade de Marília (UNIMAR), Marília, São Paulo, BrazilPostgraduate Program in Structural and Functional Interactions in Rehabilitation, School of Medicine, Universidade de Marília (UNIMAR), Marília, São Paulo, BrazilDepartment of Biochemistry and Nutrition, School of Food and Technology of Marília (FATEC), Marília, São Paulo, BrazilDepartment of Biochemistry and Pharmacology, School of Medicine, Universidade de Marília (UNIMAR), Marília, São Paulo, BrazilPostgraduate Program in Structural and Functional Interactions in Rehabilitation, School of Medicine, Universidade de Marília (UNIMAR), Marília, São Paulo, BrazilDepartment of Biochemistry and Pharmacology, School of Medicine, Universidade de Marília (UNIMAR), Marília, São Paulo, BrazilPostgraduate Program in Structural and Functional Interactions in Rehabilitation, School of Medicine, Universidade de Marília (UNIMAR), Marília, São Paulo, BrazilDepartment of Biochemistry and Pharmacology, School of Medicine, Universidade de Marília (UNIMAR), Marília, São Paulo, BrazilPostgraduate Program in Structural and Functional Interactions in Rehabilitation, School of Medicine, Universidade de Marília (UNIMAR), Marília, São Paulo, BrazilDepartment of Biochemistry and Pharmacology, School of Medicine, Universidade de Marília (UNIMAR), Marília, São Paulo, BrazilPostgraduate Program in Structural and Functional Interactions in Rehabilitation, School of Medicine, Universidade de Marília (UNIMAR), Marília, São Paulo, BrazilLaboratory of Systems Integration Pharmacology, Clinical and Regulatory Science, Research Institute for Medicines, Universidade de Lisboa (iMed.ULisboa), Lisbon, PortugalDepartment of Biochemistry and Pharmacology, School of Medicine, Universidade de Marília (UNIMAR), Marília, São Paulo, BrazilPostgraduate Program in Structural and Functional Interactions in Rehabilitation, School of Medicine, Universidade de Marília (UNIMAR), Marília, São Paulo, BrazilDepartment of Biochemistry and Nutrition, School of Food and Technology of Marília (FATEC), Marília, São Paulo, BrazilUNIMAR Charity Hospital, Universidade de Marília (UNIMAR), Marília, São Paulo, BrazilDiabetes mellitus and dyslipidemia are significant health concerns that elevate the risk of cardiovascular disease and other metabolic disorders, necessitating effective management strategies. Recent research has highlighted the potential role of dietary fats, particularly seed oils, in influencing health outcomes in these conditions. This systematic review evaluates the impact of seed oils on lipid profiles, inflammatory and oxidative markers, and glycemic control in patients with diabetes and dyslipidemia. A comprehensive search across databases, including PubMed, Scopus, Web of Science, Cochrane Library, and Google Scholar, identified studies focusing on the effects of seed oils. The studies include randomized controlled, parallel-design, double-blind, placebo-controlled, and open-label studies published in English. The quality of the studies was assessed through a detailed review process, and data were extracted to evaluate the effects of seed oils on key metabolic markers. The review included 11 studies demonstrating that seed oils derived from canola, flaxseed, and sesame seeds can positively influence lipid profiles and glycemic control while potentially modulating oxidative stress markers. The findings suggest that seed oils may benefit in managing diabetes and dyslipidemia, although the results are sometimes inconsistent. This review provides valuable insights for dietary recommendations and therapeutic strategies, highlighting the need for further research to clarify the role of seed oils in metabolic health.https://www.frontiersin.org/articles/10.3389/fnut.2025.1502815/fullseed oilsdyslipidemiatype 2 diabeteslipid profilesinflammatory markersglycemic control |
| spellingShingle | Lucas Fornari Laurindo Lucas Fornari Laurindo Lucas Fornari Laurindo Lívia Fornari Laurindo Victória Dogani Rodrigues Jéssica da Silva Camarinha Oliveira Beatriz Leme Boaro Adriano Cressoni Araújo Adriano Cressoni Araújo Elen Landgraf Guiguer Elen Landgraf Guiguer Elen Landgraf Guiguer Claudia Rucco Penteado Detregiachi Claudia Rucco Penteado Detregiachi Virgínia Maria Cavallari Strozze Catharin Virgínia Maria Cavallari Strozze Catharin Eduardo Federighi Baisi Chagas Eduardo Federighi Baisi Chagas Vitor Cavallari Strozze Catharin Vitor Cavallari Strozze Catharin Rosa Direito Sandra Maria Barbalho Sandra Maria Barbalho Sandra Maria Barbalho Sandra Maria Barbalho Evaluating the effects of seed oils on lipid profile, inflammatory and oxidative markers, and glycemic control of diabetic and dyslipidemic patients: a systematic review of clinical studies Frontiers in Nutrition seed oils dyslipidemia type 2 diabetes lipid profiles inflammatory markers glycemic control |
| title | Evaluating the effects of seed oils on lipid profile, inflammatory and oxidative markers, and glycemic control of diabetic and dyslipidemic patients: a systematic review of clinical studies |
| title_full | Evaluating the effects of seed oils on lipid profile, inflammatory and oxidative markers, and glycemic control of diabetic and dyslipidemic patients: a systematic review of clinical studies |
| title_fullStr | Evaluating the effects of seed oils on lipid profile, inflammatory and oxidative markers, and glycemic control of diabetic and dyslipidemic patients: a systematic review of clinical studies |
| title_full_unstemmed | Evaluating the effects of seed oils on lipid profile, inflammatory and oxidative markers, and glycemic control of diabetic and dyslipidemic patients: a systematic review of clinical studies |
| title_short | Evaluating the effects of seed oils on lipid profile, inflammatory and oxidative markers, and glycemic control of diabetic and dyslipidemic patients: a systematic review of clinical studies |
| title_sort | evaluating the effects of seed oils on lipid profile inflammatory and oxidative markers and glycemic control of diabetic and dyslipidemic patients a systematic review of clinical studies |
| topic | seed oils dyslipidemia type 2 diabetes lipid profiles inflammatory markers glycemic control |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2025.1502815/full |
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