3D-Printed Tablets of Nifurtimox: In Vitro and In Vivo Anti-<i>Trypanosoma cruzi</i> Studies

3D-Printed Tablets of Nifurtimox: In Vitro and In Vivo Anti-<i>Trypanosoma cruzi</i> Studies

<b>Background/Objectives</b>: Chagas disease is a neglected tropical disease caused by infection with the parasite <i>Trypanosoma cruzi</i>. Benznidazole and nifurtimox are the only approved drugs for treating this condition, but their low aqueous solubility may lead to errat...

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Bibliographic Details
Main Authors: Giselle R. Bedogni, Ana Luiza Lima, Idejan P. Gross, Tatiana Prata Menezes, Andre Talvani, Marcilio Cunha-Filho, Claudio J. Salomon
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Pharmaceutics
Subjects:
nifurtimox
film casting
hot melt extrusion
3D printing
fused deposition modeling
anti-<i>T. cruzi</i> activity
Online Access:https://www.mdpi.com/1999-4923/17/1/80
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