β-Nicotinamide mononucleotide alleviates Alcohol-Induced liver injury in a mouse model through activation of NAD+/SIRT1 signaling pathways

β-Nicotinamide mononucleotide alleviates Alcohol-Induced liver injury in a mouse model through activation of NAD+/SIRT1 signaling pathways

Abstract Background Alcoholism is a significant contributor to the development of alcoholic liver disease, for which no universally accepted and effective treatment currently exists. A precursor of NAD + , β-Nicotinamide mononucleotide (NMN), has revealed potential therapeutic benefits. However, its...

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Bibliographic Details
Main Authors: Xinxin Yang, Endian Zheng, Yuxian Lin, Haoyue Sun, Ji Zhang, Yingcong Yu
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Hereditas
Subjects:
Β-nicotinamide mononucleotide
Alcoholic hepatic injury
Inflammation
Intestinal permeability
Oxidative stress
Silent information regulator 1
Online Access:https://doi.org/10.1186/s41065-025-00529-x
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https://doi.org/10.1186/s41065-025-00529-x

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