Contamination-controlled upper gastrointestinal microbiota profiling reveals salivary-duodenal community types linked to opportunistic pathogen carriage and inflammation

Contamination-controlled upper gastrointestinal microbiota profiling reveals salivary-duodenal community types linked to opportunistic pathogen carriage and inflammation

The upper gastrointestinal (uGI) microbiota has been implicated in infectious, metabolic, and immunological conditions, yet remains poorly characterized due to invasive sampling and low microbial biomass. We developed and validated a contamination-controlled 16S rRNA gene and transcript-based protoc...

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Main Authors: Nina S. Schmidt, Elisabeth Dörner, Daniel Podlesny, Elisabeth Bohlhammer, Alena M. Bubeck, Hannah K. Ruple, Vivian Tetzlaff-Lelleck, Christian Sina, Herbert Schmidt, W. Florian Fricke
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Gut Microbes
Subjects:
Saliva
duodenum
mouse microbiota
human microbiota
microbiota transfer
extraintestinal infections
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2025.2539452
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https://www.tandfonline.com/doi/10.1080/19490976.2025.2539452

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