Impact of RAS, BRAF mutations and microsatellite status in peritoneal metastases from colorectal cancer treated with cytoreduction + HIPEC: scoping review

Impact of RAS, BRAF mutations and microsatellite status in peritoneal metastases from colorectal cancer treated with cytoreduction + HIPEC: scoping review

Background Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) has shown survival benefits in select patients with peritoneal metastases (PM) from colorectal cancer (CRC). Molecular alterations, particularly RAS/BRAF mutations and Microsatellite Instability (M...

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Bibliographic Details
Main Authors: Valentina Zucchini, Fabrizio D’Acapito, Ilario Giovanni Rapposelli, Massimo Framarini, Daniela Di Pietrantonio, Riccardo Turrini, Eleonora Pozzi, Giorgio Ercolani
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:International Journal of Hyperthermia
Subjects:
Colorectal cancer
peritoneal metastasis
cytoreductive surgery
HIPEC
RAS/BRAF mutations
microsatellite instability
Online Access:https://www.tandfonline.com/doi/10.1080/02656736.2025.2479527
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https://www.tandfonline.com/doi/10.1080/02656736.2025.2479527

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