Substantial spillover burden of rat hepatitis E virus in humans

Abstract The emergence of Rocahepevirus ratti genotype 1 (rat hepatitis E virus; rat HEV) in humans presents an unprecedented threat; however, the risk of rat HEV transmission to humans is not well understood. Here, we report the “Distinguishing Antibody Response Elicitation (DARE)” method, which di...

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Main Authors: Zihao Chen, Lifeng Wang, Yongde Zhang, Guanghui Li, Jiaxiang Yin, Jingyan Fan, Tianxu Liu, Han Wu, Yue Huang, Wenhui Huang, Donglin Liu, Xiaoxiang Zheng, Xia Zang, Xingcheng Huang, Liuwei Song, Shunhua Wen, Jiayu Li, Dong Ying, Mujin Fang, Yingbin Wang, Ting Wu, Siddharth Sridhar, Jun Zhang, Ningshao Xia, Lin Wang, Yihan Lu, Zizheng Zheng
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59345-6
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