Improvement in body composition of Japanese participants with Prader-Willi syndrome following somatropin treatment: an open-label, multi cohort Phase 3 study

Improvement in body composition of Japanese participants with Prader-Willi syndrome following somatropin treatment: an open-label, multi cohort Phase 3 study

Recombinant human growth hormone (GH; somatropin) treatment has beneficial effects on body composition in patients with Prader-Willi syndrome (PWS). However, this treatment option is limited to children in most countries and to children with short stature in countries such as the USA and Japan. The...

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Bibliographic Details
Main Authors: Masanobu Kawai, Nobuyuki Murakami, Reiko Horikawa, Koji Muroya, Yasuko Fujisawa, Yuko Hoshino, Akifumi Okayama, Takahiro Sato, Nozomi Ebata, Tsutomu Ogata
Format: Article
Language:English
Published: The Japan Endocrine Society 2025-08-01
Series:Endocrine Journal
Subjects:
prader-willi syndrome
somatropin
growth hormone
adult
body composition
Online Access:https://www.jstage.jst.go.jp/article/endocrj/72/8/72_EJ24-0659/_html/-char/en
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https://www.jstage.jst.go.jp/article/endocrj/72/8/72_EJ24-0659/_html/-char/en

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