Utilizing NF-κB Signaling in Porcine Epithelial Cells to Identify a Plant-Based Additive for the Development of a Porcine Epidemic Diarrhea Virus Vaccine

Utilizing NF-κB Signaling in Porcine Epithelial Cells to Identify a Plant-Based Additive for the Development of a Porcine Epidemic Diarrhea Virus Vaccine

The nuclear factor-kappa B (NF-κB) signaling pathway plays a crucial role in regulating immune responses in epithelial cells. In this study, we established a porcine epithelial NF-κB reporter cell line (PK15-KBR) as an in vitro platform to screen plant-based extracts for their potential use as vacci...

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Bibliographic Details
Main Authors: Nguyen-Thanh Hoa, Haroon Afzal, Thu-Dung Doan, Asad Murtaza, Chia-Hung Yen, Yao-Chi Chung
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Veterinary Sciences
Subjects:
NF-κB signaling pathway
porcine epidemic diarrhea virus (PEDV)
epithelial cells
PK15-KBR cell line
plant extracts
in vitro tool
Online Access:https://www.mdpi.com/2306-7381/12/2/181
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