miR‐181a/b downregulation exerts a protective action on mitochondrial disease models

miR‐181a/b downregulation exerts a protective action on mitochondrial disease models

Abstract Mitochondrial diseases (MDs) are a heterogeneous group of devastating and often fatal disorders due to defective oxidative phosphorylation. Despite the recent advances in mitochondrial medicine, effective therapies are still not available for these conditions. Here, we demonstrate that the...

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Main Authors: Alessia Indrieri, Sabrina Carrella, Alessia Romano, Alessandra Spaziano, Elena Marrocco, Erika Fernandez‐Vizarra, Sara Barbato, Mariateresa Pizzo, Yulia Ezhova, Francesca M Golia, Ludovica Ciampi, Roberta Tammaro, Jorge Henao‐Mejia, Adam Williams, Richard A Flavell, Elvira De Leonibus, Massimo Zeviani, Enrico M Surace, Sandro Banfi, Brunella Franco
Format: Article
Language:English
Published: Springer Nature 2019-04-01
Series:EMBO Molecular Medicine
Subjects:
LHON
microRNA
miR‐181
mitochondrial disease
neurodegeneration
Online Access:https://doi.org/10.15252/emmm.201708734
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https://doi.org/10.15252/emmm.201708734

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