Diagnostic performance of circulating EpCAM+ and CD45+ extracellular vesicles in platinum-sensitivity in high-grade serous ovarian cancer: a pilot study

Diagnostic performance of circulating EpCAM+ and CD45+ extracellular vesicles in platinum-sensitivity in high-grade serous ovarian cancer: a pilot study

Abstract Background Platinum-resistant high-grade serous ovarian cancer (HGSOC) is a fatal disease. The main goal of current study is to develop new strategies to predict platinum resistance, moving towards personalized therapy. Currently, there are no validated biomarkers able to predict at diagnos...

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Main Authors: Chiara Tersigni, Marianna Onori, Alexia Buzzonetti, Arianna Ferrante, Andrea Fattorossi, Alessandra Battaglia, Giacomo Corrado, Caterina Neri, Giuliana Beneduce, Fabio Sannino, Alessandro Petrecca, Giovanni Scambia, Anna Fagotti
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Journal of Ovarian Research
Subjects:
EpCAM
CD45
HGSOC
Chemoresistance
Extracellular vesicles
Online Access:https://doi.org/10.1186/s13048-025-01656-9
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https://doi.org/10.1186/s13048-025-01656-9

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