Integration of bulk RNA-seq and scRNA-seq reveals transcriptomic signatures associated with deep vein thrombosis

Integration of bulk RNA-seq and scRNA-seq reveals transcriptomic signatures associated with deep vein thrombosis

BackgroundDeep vein thrombosis (DVT) is a prevalent peripheral vascular disease. The intricate and multifaceted nature of the associated mechanisms hinders a comprehensive understanding of disease-relevant targets. This study aimed to identify and examine the most distinctive genes linked to DVT.Met...

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Main Authors: Bao-ze Pan, Ming-jun Jiang, Li-ming Deng, Jie Chen, Xian-peng Dai, Zi-xuan Wu, Zhi-he Deng, Dong-yang Luo, Yang-yi-jing Wang, Dan Ning, Guo-zuo Xiong, Guo-shan Bi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Genetics
Subjects:
deep vein thrombosis
venous thromboembolism
WGCNA
bulk RNA-seq
ScRNA-seq
machine learning
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2025.1551879/full
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https://www.frontiersin.org/articles/10.3389/fgene.2025.1551879/full

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