The Dual Role of cGAS-STING Signaling in COVID-19: Implications for Therapy

The Dual Role of cGAS-STING Signaling in COVID-19: Implications for Therapy

The progression of COVID-19 involves a sophisticated and intricate interplay between the SARS-CoV-2 virus and the host’s immune response. The immune system employs both innate and adaptive mechanisms to combat infection. Innate immunity initiates the release of interferons (IFNs) and pro-inflammator...

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Bibliographic Details
Main Authors: Daniele Castro di Flora, João Paulo Zanardini Lara, Aline Dionizio, Marília Afonso Rabelo Buzalaf
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Cells
Subjects:
SARS-CoV-2 infection
COVID-19
cGAS–STING pathway
innate immunity
Online Access:https://www.mdpi.com/2073-4409/14/5/362
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