TFRC promotes the proliferation, migration, and invasion of osteosarcoma cells by increasing the intracellular iron content and RRM2 expression

BackgroundMultiple studies have shown that the transferrin receptor (TFRC) is highly expressed in various tumors, and it has been recognized as a cancer biomarker. However, its role in osteosarcoma(OS) has rarely been studied. The purpose of this study was to explore the role and mechanism of TFRC i...

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Bibliographic Details
Main Authors: Guoqing Ren, Jian Zhou, Yong Su, Qiang Yang, Jianmin Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1567216/full
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