Deciphering the role of Wnt/β-catenin and miR-214 in knee osteoarthritis: molecular and clinical insights

Deciphering the role of Wnt/β-catenin and miR-214 in knee osteoarthritis: molecular and clinical insights

IntroductionUnderstanding the molecular mechanism underlying the pathogenesis of knee osteoarthritis (KOA) may be beneficial in fetching new therapeutics. Our study aims to investigate the implication of Wnt/ β-catenin pathway in development of KOA by detection of the downstream target genes and the...

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Main Authors: Waad A. Samman, Esraa M. Mosalam, Dalia S. Saif, Mahmoud S. Abdallah, Abdel-Aziz A. Zidan, Amany Said Sallam, Shimaa Abdelsattar, Fatma Omar Khalil, Amany E. Elashkar, Somia Mokabel Mohamed, Mohamed Al-Ghannam, Hend E. Abo Mansour
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Pharmacology
Subjects:
knee osteoarthritis
miR-214
Wnt/β-catenin
PGSK3β
WOMAC score
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1507693/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1507693/full

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