Rare Copy Number Variants Reveal Critical Cell Types and Periods of Brain Development in Neurodevelopmental Disorders

Background: Multiple copy number variations (CNVs) in the human genome are associated with neurodevelopmental disorders (NDDs). Their markedly larger effect sizes and penetrance than common risk variants make them invaluable for investigating the etiology of NDDs. Methods: We integrated >1 millio...

Full description

Saved in:
Bibliographic Details
Main Authors: Susmita Malwade, Carl M. Sellgren, Navneet A. Vasistha, Konstantin Khodosevich
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Biological Psychiatry Global Open Science
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667174325000497
Tags: Add Tag
No Tags, Be the first to tag this record!