Systematic Review of Pharmacogenetics of Immunosuppressants in Heart Transplantation

Systematic Review of Pharmacogenetics of Immunosuppressants in Heart Transplantation

The standard immunosuppressive treatments in heart transplantation are calcineurin inhibitors, corticosteroids, and antimetabolite agents or inhibitors of the mammalian target of rapamycin. Pharmacogenetic studies show the impact on clinical course of genetic variability in genes that encode transpo...

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Main Authors: Juan Eduardo Megías-Vericat, Tomás Palanques-Pastor, Mireya Fernández-Sánchez, Eduardo Guerrero-Hurtado, Mayte Gil-Candel, Antonio Solana-Altabella, Octavio Ballesta-López, María Centelles-Oria, Javier García-Pellicer, José Luis Poveda-Andrés
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Cardiogenetics
Subjects:
tacrolimus
cyclosporine
mycophenolic acid
cardiac transplant
precision medicine
CYP3A5
Online Access:https://www.mdpi.com/2035-8148/15/2/18
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