An acidic microenvironment promotes lymphatic metastasis of melanoma by Thy-1 in endothelial cells and integrin αvβ3 in tumor cells
Abstract Melanoma tissues exhibit an acidic microenvironment compared with that of surrounding normal tissues. However, the effects of acidic conditions on the lymphatic metastasis, a crucial prognostic factor for patients with melanoma, are unclear. In the present study, we aimed to investigate the...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-04-01
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| Series: | Discover Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s12672-025-02276-x |
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