Identification and validation of diagnostic biomarkers for temporal lobe epilepsy related to ferroptosis and potential therapeutic targets

Identification and validation of diagnostic biomarkers for temporal lobe epilepsy related to ferroptosis and potential therapeutic targets

Abstract Ferroptosis pathway activation is potentially correlated with temporal lobe epilepsy (TLE). However, the diagnostic significance and mechanism of ferroptosis-related genes (FRGs) in TLE require further investigation. A comprehensive analysis of the GSE134697 dataset from the Gene Expression...

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Bibliographic Details
Main Authors: Dai Shi, Jingxuan Li, Zhenpeng Niu, Likun Wang, Siying Ren, Wen Gu, Hui Yang, Hong Xue, Guofeng Wu
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Temporal lobe epilepsy
Ferroptosis-related genes
Biomarkers
Immune cell infiltration
Bioinformatics
Online Access:https://doi.org/10.1038/s41598-025-89390-6
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https://doi.org/10.1038/s41598-025-89390-6

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