From Quiescence to Activation: The Reciprocal Regulation of Ras and Rho Signaling in Hepatic Stellate Cells

From Quiescence to Activation: The Reciprocal Regulation of Ras and Rho Signaling in Hepatic Stellate Cells

Chronic liver diseases are marked by persistent inflammation and can evolve into liver fibrosis, cirrhosis, and hepatocellular carcinoma. In an affected liver, hepatic stellate cells (HSCs) transition from a quiescent to an activated state and adopt a myofibroblast-like cell phenotype. While these a...

Full description

Saved in:
Bibliographic Details
Main Authors: Saeideh Nakhaei-Rad, Silke Pudewell, Amin Mirzaiebadizi, Kazem Nouri, Doreen Reichert, Claus Kordes, Dieter Häussinger, Mohammad Reza Ahmadian
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Cells
Subjects:
chronic liver disease
cirrhosis
hepatic stellate cells
liver fibrosis
quiescent state
Ras GTPases
Online Access:https://www.mdpi.com/2073-4409/14/9/674
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/2073-4409/14/9/674

Similar Items