Effects of acute low intensity aerobics and blueberry juice on arterial stiffness in young adults

Abstract Arterial stiffness, a cardiovascular disease (CVD) predictor starting from youth, is under-researched in young adults. Low-intensity aerobic exercise (LAE) is generally more accessible than higher-intensity exercise and may be more sustainable for young individuals. Blueberries, renowned fo...

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Main Authors: Ruisi Wu, Huali Yu, Jiayuan Xu, Zhiqiang Tan, Yongsheng Lan, Dongfang Shi
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:npj Science of Food
Online Access:https://doi.org/10.1038/s41538-025-00408-9
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author Ruisi Wu
Huali Yu
Jiayuan Xu
Zhiqiang Tan
Yongsheng Lan
Dongfang Shi
author_facet Ruisi Wu
Huali Yu
Jiayuan Xu
Zhiqiang Tan
Yongsheng Lan
Dongfang Shi
author_sort Ruisi Wu
collection DOAJ
description Abstract Arterial stiffness, a cardiovascular disease (CVD) predictor starting from youth, is under-researched in young adults. Low-intensity aerobic exercise (LAE) is generally more accessible than higher-intensity exercise and may be more sustainable for young individuals. Blueberries, renowned for vascular health benefits, may reduce arterial stiffness. This study examines the effects of LAE and blueberry juice on arterial stiffness in 48 young adults. Participants were randomized into LAE, low-, mid-, or high-volume blueberry juice (LB, MB, HB), LAE + LB, LAE + MB, LAE + HB, and control groups. Arterial stiffness was measured at baseline and at 15-, 30-, 45-, and 60 min post-intervention. Blood samples were collected pre-intervention and 30-min post-intervention for metabolomic analysis. Repeated ANOVA revealed LAE + MB significantly reduced arterial stiffness. Metabolomic analysis revealed changes in linoleic acid, sphingolipid, phenylalanine, nicotinate and nicotinamide, glycerophospholipid, and lysine degradation metabolic pathways. These findings suggest a feasible exercise-diet strategy for CVD prevention in young adults and provide metabolic insights into the mechanisms.
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issn 2396-8370
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publishDate 2025-04-01
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spelling doaj-art-f8cedd22bd9d4c77af8ccb3ff4aaf0972025-08-20T03:04:53ZengNature Portfolionpj Science of Food2396-83702025-04-01911810.1038/s41538-025-00408-9Effects of acute low intensity aerobics and blueberry juice on arterial stiffness in young adultsRuisi Wu0Huali Yu1Jiayuan Xu2Zhiqiang Tan3Yongsheng Lan4Dongfang Shi5Changchun Normal University, ChangchunKey Laboratory of Molecular Epigenetics, Ministry of Education and Institute of Cytology and Genetics, Northeast Normal UniversityTonghua Changbaishan Wild Economic Plant Research Institute, TonghuaTonghua Changbaishan Wild Economic Plant Research Institute, TonghuaChangchun Normal University, ChangchunChangchun Normal University, ChangchunAbstract Arterial stiffness, a cardiovascular disease (CVD) predictor starting from youth, is under-researched in young adults. Low-intensity aerobic exercise (LAE) is generally more accessible than higher-intensity exercise and may be more sustainable for young individuals. Blueberries, renowned for vascular health benefits, may reduce arterial stiffness. This study examines the effects of LAE and blueberry juice on arterial stiffness in 48 young adults. Participants were randomized into LAE, low-, mid-, or high-volume blueberry juice (LB, MB, HB), LAE + LB, LAE + MB, LAE + HB, and control groups. Arterial stiffness was measured at baseline and at 15-, 30-, 45-, and 60 min post-intervention. Blood samples were collected pre-intervention and 30-min post-intervention for metabolomic analysis. Repeated ANOVA revealed LAE + MB significantly reduced arterial stiffness. Metabolomic analysis revealed changes in linoleic acid, sphingolipid, phenylalanine, nicotinate and nicotinamide, glycerophospholipid, and lysine degradation metabolic pathways. These findings suggest a feasible exercise-diet strategy for CVD prevention in young adults and provide metabolic insights into the mechanisms.https://doi.org/10.1038/s41538-025-00408-9
spellingShingle Ruisi Wu
Huali Yu
Jiayuan Xu
Zhiqiang Tan
Yongsheng Lan
Dongfang Shi
Effects of acute low intensity aerobics and blueberry juice on arterial stiffness in young adults
npj Science of Food
title Effects of acute low intensity aerobics and blueberry juice on arterial stiffness in young adults
title_full Effects of acute low intensity aerobics and blueberry juice on arterial stiffness in young adults
title_fullStr Effects of acute low intensity aerobics and blueberry juice on arterial stiffness in young adults
title_full_unstemmed Effects of acute low intensity aerobics and blueberry juice on arterial stiffness in young adults
title_short Effects of acute low intensity aerobics and blueberry juice on arterial stiffness in young adults
title_sort effects of acute low intensity aerobics and blueberry juice on arterial stiffness in young adults
url https://doi.org/10.1038/s41538-025-00408-9
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