MACAW: a method for semi-automatic detection of errors in genome-scale metabolic models
Abstract Genome-scale metabolic models (GSMMs) are used to predict metabolic fluxes, with applications ranging from identifying novel drug targets to engineering microbial metabolism. Erroneous or missing reactions, scattered throughout densely interconnected networks, are a limiting factor in these...
Saved in:
| Main Authors: | Devlin C. Moyer, Justin Reimertz, Daniel Segrè, Juan I. Fuxman Bass |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-03-01
|
| Series: | Genome Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13059-025-03533-6 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Strategy for Optimizing Vitamin B12 Production in <i>Pseudomonas putida</i> KT2440 Using Metabolic Modeling
by: Thomaz Satuye Prieto-de Lima, et al.
Published: (2024-11-01) -
Integration of clinical data with a genome‐scale metabolic model of the human adipocyte
by: Adil Mardinoglu, et al.
Published: (2013-03-01) -
Auxotrophy-based curation improves the consensus genome-scale metabolic model of yeast
by: Siyu Han, et al.
Published: (2024-12-01) -
Personalized whole‐body models integrate metabolism, physiology, and the gut microbiome
by: Ines Thiele, et al.
Published: (2020-05-01) -
In silico identification of switching nodes in metabolic networks
by: Mairet, Francis
Published: (2024-10-01)