MACAW: a method for semi-automatic detection of errors in genome-scale metabolic models

Abstract Genome-scale metabolic models (GSMMs) are used to predict metabolic fluxes, with applications ranging from identifying novel drug targets to engineering microbial metabolism. Erroneous or missing reactions, scattered throughout densely interconnected networks, are a limiting factor in these...

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Bibliographic Details
Main Authors: Devlin C. Moyer, Justin Reimertz, Daniel Segrè, Juan I. Fuxman Bass
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-025-03533-6
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