Alteration of telomere length and mtDNA copy number in interstitial lung disease associated with rheumatoid arthritis

Alteration of telomere length and mtDNA copy number in interstitial lung disease associated with rheumatoid arthritis

Interstitial lung disease (ILD) is a common extra-articular manifestation of rheumatoid arthritis (RA). The inflammatory response in lung disease is characterized by severe oxidative stress, which enhances cellular senescence. Telomeric shortening and mitochondria dysregulation represent two hallmar...

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Main Authors: Giada De Benedittis, Andrea Latini, Chiara Morgante, Chiara Bonini, Eneida Cela, Barbara Kroegler, Alessandra Luciano, Marcello Chiocchi, Francesco Cavalli, Josuel Ora, Paola Rogliani, Giuseppe Novelli, Cinzia Ciccacci, Maria Sole Chimenti, Paola Conigliaro, Paola Borgiani
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Autoimmunity
Subjects:
Rheumatoid arthritis
interstitial lung disease
telomere length
mtDNA
gene expression
Online Access:https://www.tandfonline.com/doi/10.1080/08916934.2025.2473741
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https://www.tandfonline.com/doi/10.1080/08916934.2025.2473741

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