Peripheral neuropathy as initial manifestation of Churg-Strauss Syndrome
Peripheral neuropathy is a well-known complication of primary systemic vasculitides that are characterized by inflammatory cell infiltration causing necrosis of blood vessels. Neurological complications in eosinophilic granulomatosis with polyangiitis (EGPA), previously known as Churg-Strauss syndro...
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Edizioni FS
2020-03-01
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| Series: | Journal of Health and Social Sciences |
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| _version_ | 1832595583975555072 |
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| author | Antonio Villa Marianna Gregorio Francesca Bassi Ignazio Santilli |
| author_facet | Antonio Villa Marianna Gregorio Francesca Bassi Ignazio Santilli |
| author_sort | Antonio Villa |
| collection | DOAJ |
| description | Peripheral neuropathy is a well-known complication of primary systemic vasculitides that are characterized by inflammatory cell infiltration causing necrosis of blood vessels. Neurological complications in eosinophilic granulomatosis with polyangiitis (EGPA), previously known as Churg-Strauss syndrome, can be seen in 60-70% of cases, and in a portion of them neurological dysfunction may precede the involvement of other organs. An early recognition of this entity is the key to successful treatment and positive outcome. We report a case of Churg-Strauss syndrome in a young man with signs of rapidly evolving peripheral neuropathy. The diagnosis was established based on the hypereosinophilia, nasal polyposis, a positive biopsy and ANCA serology, without a history of asthma. In this case report, the peripheral neuropathy was the initial manifestation of the Churg-Strauss syndrome. |
| format | Article |
| id | doaj-art-f858c0f683404491ba1b65a258c8669b |
| institution | Kabale University |
| issn | 2499-2240 2499-5886 |
| language | English |
| publishDate | 2020-03-01 |
| publisher | Edizioni FS |
| record_format | Article |
| series | Journal of Health and Social Sciences |
| spelling | doaj-art-f858c0f683404491ba1b65a258c8669b2025-01-18T18:20:29ZengEdizioni FSJournal of Health and Social Sciences2499-22402499-58862020-03-015114114810.19204/2019/prph5Peripheral neuropathy as initial manifestation of Churg-Strauss SyndromeAntonio Villa Marianna Gregorio0Francesca Bassi1 Ignazio Santilli2Medical Doctor, Department of Emergency, ASST Monza, Desio Hospital, Monza, Italy Medical Doctor, Department of Internal Medicine, ASST Monza, Desio Hospital, Monza, Italy Medical Doctor, Department of Neurology, ASST Monza, Desio Hospital, Monza, Italy.Peripheral neuropathy is a well-known complication of primary systemic vasculitides that are characterized by inflammatory cell infiltration causing necrosis of blood vessels. Neurological complications in eosinophilic granulomatosis with polyangiitis (EGPA), previously known as Churg-Strauss syndrome, can be seen in 60-70% of cases, and in a portion of them neurological dysfunction may precede the involvement of other organs. An early recognition of this entity is the key to successful treatment and positive outcome. We report a case of Churg-Strauss syndrome in a young man with signs of rapidly evolving peripheral neuropathy. The diagnosis was established based on the hypereosinophilia, nasal polyposis, a positive biopsy and ANCA serology, without a history of asthma. In this case report, the peripheral neuropathy was the initial manifestation of the Churg-Strauss syndrome.churg-strauss syndrome; eosinophilic granulomatosis with polyangiitis; eosinophilic vasculitis; peripheral neuropathy. |
| spellingShingle | Antonio Villa Marianna Gregorio Francesca Bassi Ignazio Santilli Peripheral neuropathy as initial manifestation of Churg-Strauss Syndrome Journal of Health and Social Sciences churg-strauss syndrome; eosinophilic granulomatosis with polyangiitis; eosinophilic vasculitis; peripheral neuropathy. |
| title | Peripheral neuropathy as initial manifestation of Churg-Strauss Syndrome |
| title_full | Peripheral neuropathy as initial manifestation of Churg-Strauss Syndrome |
| title_fullStr | Peripheral neuropathy as initial manifestation of Churg-Strauss Syndrome |
| title_full_unstemmed | Peripheral neuropathy as initial manifestation of Churg-Strauss Syndrome |
| title_short | Peripheral neuropathy as initial manifestation of Churg-Strauss Syndrome |
| title_sort | peripheral neuropathy as initial manifestation of churg strauss syndrome |
| topic | churg-strauss syndrome; eosinophilic granulomatosis with polyangiitis; eosinophilic vasculitis; peripheral neuropathy. |
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