Sprouty4, an FGF inhibitor, displays cyclic gene expression under the control of the notch segmentation clock in the mouse PSM.

<h4>Background</h4>During vertebrate embryogenesis, somites are generated at regular intervals, the temporal and spatial periodicity of which is governed by a gradient of fibroblast growth factor (FGF) and/or Wnt signaling activity in the presomitic mesoderm (PSM) in conjunction with osc...

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Bibliographic Details
Main Authors: Shinichi Hayashi, Taiju Shimoda, Masato Nakajima, Yuki Tsukada, Yuichi Sakumura, J Kim Dale, Miguel Maroto, Kenji Kohno, Takaaki Matsui, Yasumasa Bessho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0005603&type=printable
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