Pretreatment with growth differentiation factor 15 augments cardioprotection by mesenchymal stem cells in myocardial infarction by improving their survival

Pretreatment with growth differentiation factor 15 augments cardioprotection by mesenchymal stem cells in myocardial infarction by improving their survival

Abstract Background The clinical application of mesenchymal stem cells (MSCs) in myocardial infarction (MI) is severely hampered by their poor survival. Pretreatment is a key strategy that has been adopted to promote their therapeutic efficacy. This study aimed to investigate the benefit of growth d...

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Main Authors: Xinran Huang, Xiaoting Liang, Qian Han, Ying Shen, Jiaqi Chen, Ziqi Li, Jie Qiu, Xiaoyan Gao, Yimei Hong, Fang Lin, Weifeng Li, Xin Li, Yuelin Zhang
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cells
Myocardial infarction
Growth differentiation factor 15
Cell survival
Mitochondrion
Online Access:https://doi.org/10.1186/s13287-024-04030-6
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https://doi.org/10.1186/s13287-024-04030-6

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