Anti-PD-1 therapy activates tumoricidic properties of NKT cells and contributes to the overall deceleration of tumor progression in a model of murine mammary carcinoma

Anti-PD-1 therapy activates tumoricidic properties of NKT cells and contributes to the overall deceleration of tumor progression in a model of murine mammary carcinoma

Background/Aim. Immune checkpoint therapy is a well-established therapeutic approach in the treatment of malignant diseases and is thought to be mostly based on facilitating the adaptive immune response. However, the cells of the innate immune response, such as natural killer T (NKT) cells, might al...

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Main Authors: Jovanović Marina, Gajović Nevena, Jurišević Milena, Sekulić Sofija, Arsenijević Nebojša, Jocić Miodrag, Jovanović Milan, Lukić Ružica, Jovanović Ivan, Radovanović Dragče
Format: Article
Language:English
Published: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2022-01-01
Series:Vojnosanitetski Pregled
Subjects:
antineoplastic agents
breast neoplasms
immunomodulation
killer cell, natural
macrophages
mice
Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2022/0042-84502100039J.pdf
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http://www.doiserbia.nb.rs/img/doi/0042-8450/2022/0042-84502100039J.pdf

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