Design and screening of novel molecular compounds targeting lactate dehydrogenase of Babesia microti

Design and screening of novel molecular compounds targeting lactate dehydrogenase of Babesia microti

Abstract Background Human babesiosis is caused by several species within the Babesia genus, primarily Babesia microti, Babesia duncani, and Babesia divergens, all of which infect human red blood cells (RBCs). Clinically, the disease manifests with symptoms such as fever, anemia, jaundice, and hemogl...

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Main Authors: Wanxin Luo, Long Yu, Shiyu Lu, Yuxin Yu, Yidan Bai, Sen Wang, Dongfang Li, Zhen Han, Yaxin Zheng, Fangjie Li, Junlong Zhao, Lan He
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Parasites & Vectors
Subjects:
Babesia microti
Lactate dehydrogenase
Compound
Computer-aided drug design
Surface plasmon resonance
Online Access:https://doi.org/10.1186/s13071-024-06623-9
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https://doi.org/10.1186/s13071-024-06623-9

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