Exosomes derived from platelet-rich plasma alleviate synovial inflammation by enhancing synovial lymphatic function

Exosomes derived from platelet-rich plasma alleviate synovial inflammation by enhancing synovial lymphatic function

Abstract Background Synovial inflammation is a pivotal factor in the pathogenesis of osteoarthritis (OA). Platelet-rich plasma-derived Exosomes (PRP-Exos), known for their low immunogenicity, have demonstrated efficacy in modulating chondrocyte function. However, the specific effects and mechanisms...

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Main Authors: Bo Liao, Yu Tian, Mengtong Guan, Wang Han, Weiwei Yi, Kaiting Li, Xiaoliang Yang, Yajuan Niu, Bin Zhang, Peiyu Teng, Dingqun Bai, Liang Kuang, Ying Zhu, Xiaoyu Han
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Nanobiotechnology
Subjects:
Platelet-rich plasma-derived exosome
Synovial inflammation
Lymphatic vessel
Online Access:https://doi.org/10.1186/s12951-025-03591-9
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https://doi.org/10.1186/s12951-025-03591-9

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