Sea buckthorn-derived extracellular vesicles foster bone regeneration through aau-miR168-mediated pathways

Sea buckthorn-derived extracellular vesicles foster bone regeneration through aau-miR168-mediated pathways

Abstract Background Plant-derived extracellular vesicles (P-EVs) possess remarkable therapeutic potential, yet the regenerative capabilities of sea buckthorn-derived extracellular vesicles (SAEVs) remain underexplored. This study aims to elucidate the osteogenic and bone-healing properties of SAEVs....

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Main Authors: Mai Zhao, Xiaolin Chen, Wenyan Wang, Mengying Li, Hui Zhang, Xiuqun Zou, Jiamin Wang, Qian Cong, Xingyuan Ma, Zhaoyuan Hou, Haodong Lin, Hao Jia
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Stem Cell Research & Therapy
Subjects:
Bone marrow mesenchymal stromal cell
Extracellular vesicle
Osteocalcin
Osteogenesis
Runx2
Sea buckthorn
Online Access:https://doi.org/10.1186/s13287-025-04373-8
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https://doi.org/10.1186/s13287-025-04373-8

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