Exploring WNT pathway dysregulation in serrated colorectal cancer for improved diagnostic and therapeutic strategies

BackgroundSerrated colorectal cancer (SCC) is a rare and aggressive subtype of colorectal cancer. Identifying SCC is crucial due to its high mortality rate and limited therapeutic options. Traditional methods to identify BRAF hotspot mutations and MLH1 methylation are insufficient in clinical practi...

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Bibliographic Details
Main Authors: Fengzhi Zhu, Helen Hoi Ning Yan, Yin Tong, Yueliang Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2025.1586867/full
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