Tetranucleotide frequencies differentiate genomic boundaries and metabolic strategies across environmental microbiomes

ABSTRACT Microbiomes are constrained by physicochemical conditions, nutrient regimes, and community interactions across diverse environments, yet genomic signatures of this adaptation remain unclear. Metagenome sequencing is a powerful technique to analyze genomic content in the context of natural e...

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Main Authors: Matthew Kellom, Maureen Berg, I-Min A. Chen, Ken Chu, Alicia Clum, Marcel Huntemann, Natalia N. Ivanova, Nikos C. Kyrpides, Supratim Mukherjee, T. B. K. Reddy, Simon Roux, Rekha Seshadri, Gitta Szabo, Neha J. Varghese, Tanja Woyke, Emiley A. Eloe-Fadrosh
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Series:mSystems
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Online Access:https://journals.asm.org/doi/10.1128/msystems.01744-24
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