Mediator MED23 controls oligodendrogenesis and myelination by modulating Sp1/P300-directed gene programs
Abstract Gaining the molecular understanding for myelination development and regeneration has been a long-standing goal in neurological research. Mutations in the transcription cofactor Mediator Med23 subunit are often associated with intellectual disability and white matter defects, although the pr...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2024-10-01
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| Series: | Cell Discovery |
| Online Access: | https://doi.org/10.1038/s41421-024-00730-8 |
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