Targeting Oncofoetal Chondroitin Sulphate Allows Identification of Tumour‐Derived Extracellular Vesicles

Targeting Oncofoetal Chondroitin Sulphate Allows Identification of Tumour‐Derived Extracellular Vesicles

ABSTRACT Tumour‐derived extracellular vesicles (tdEVs) are widely studied for their contribution to tumour progression and metastasis. These studies are hampered by the lack of specific markers to identify the tdEVs. Here, we show that oncofoetal chondroitin sulphate, a malignancy‐associated glycosa...

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Main Authors: Agustin Enciso‐Martinez, Caroline Løppke, Joyce J. Koene, Jade Ebbelaar, Meike van der Geest, Mandy Los, Emma P. E. M. Boerrigter, Robert Dagil, Tobias Gustavsson, Elena E. Vidal‐Calvo, Ton G. van Leeuwen, Roman I. Koning, Nick van Es, Ali Salanti, Edwin van der Pol, Rienk Nieuwland, Mette Ø. Agerbæk, Peter ten Dijke
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Journal of Extracellular Vesicles
Subjects:
cancer
extracellular vesicles
liquid biopsy
pancreatic adenocarcinoma
VAR2CSA
biomarker
Online Access:https://doi.org/10.1002/jev2.70106
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https://doi.org/10.1002/jev2.70106

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