Gut commensal Parabacteroides distasonis exerts neuroprotective effects in acute ischemic stroke with hyperuricemia via regulating gut microbiota-gut-brain axis

Gut commensal Parabacteroides distasonis exerts neuroprotective effects in acute ischemic stroke with hyperuricemia via regulating gut microbiota-gut-brain axis

Abstract Background Hyperuricemia is considered as an independent risk factor for acute ischemic stroke (AIS), and some AIS patients are accompanied by an increase in serum uric acid. Recent studies have highlighted the important role of gut microbiota in both hyperuricemia and AIS, but there is lit...

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Bibliographic Details
Main Authors: Hongming Wei, Lu Zhan, Xinhuang Lv, Yan Lin, Jie Zheng, Wenwen Yang, Jiaming Liu, Jing Sun, Songfang Chen
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Translational Medicine
Subjects:
Hyperuricemia associated stroke
Gut microbiota
P. distasonis
Vascular damage
Uric acid
Online Access:https://doi.org/10.1186/s12967-024-05800-9
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https://doi.org/10.1186/s12967-024-05800-9

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