Real-world data analysis for factors influencing the quality check status in FoundationOne CDx cancer genomic profiling tests

Real-world data analysis for factors influencing the quality check status in FoundationOne CDx cancer genomic profiling tests

Abstract Comprehensive genomic profiling (CGP) testing is used worldwide for personalized cancer treatment. Unstained slides from formalin-fixed paraffin-embedded (FFPE) blocks are required for tissue-based CGP testing. However, the use of low quality FFPE specimens can result in testing failure or...

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Bibliographic Details
Main Authors: Hiroaki Niitsu, Hikaru Nakahara, Katsunari Ishida, Yoshie Kaneko, C. Nelson Hayes, Koji Arihiro, Takao Hinoi
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Cancer genomic profiling
FoundationOne CDx
Quality check
Solid tumors
Online Access:https://doi.org/10.1038/s41598-025-85846-x
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https://doi.org/10.1038/s41598-025-85846-x

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