Building a pre-surgical multiparametric-MRI-based morphologic, qualitative, semiquantitative, first and high-order radiomic predictive treatment response model for undifferentiated pleomorphic sarcoma to replace RECIST

Building a pre-surgical multiparametric-MRI-based morphologic, qualitative, semiquantitative, first and high-order radiomic predictive treatment response model for undifferentiated pleomorphic sarcoma to replace RECIST

Abstract Background Undifferentiated pleomorphic sarcoma (UPS) is the largest subgroup of soft-tissue sarcomas. It demonstrates post-therapeutic hemosiderin deposition, granulation tissue formation, fibrosis, and calcification. Our research aims to establish the multiparametric MRI (mp-MRI) value fo...

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Main Authors: Raul F. Valenzuela, Elvis Duran-Sierra, Mathew Antony, Behrang Amini, Sam Lo, Keila E. Torres, Robert S. Benjamin, Jingfei Ma, Ken-Pin Hwang, R. Jason Stafford, Dejka Araujo, Andrew J. Bishop, Ravin Ratan, Wei-Lien Wang, Jossue Espinoza, Pia V. Valenzuela, Chengyue Wu, John E. Madewell, William A. Murphy, Colleen M. Costelloe
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Cancer Imaging
Subjects:
Soft tissue sarcoma (STS)
Undifferentiated pleomorphic sarcoma (UPS)
Pathology-assessed treatment effect (PATE)
Multiparametric MRI
Radiomics
Online Access:https://doi.org/10.1186/s40644-025-00873-1
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https://doi.org/10.1186/s40644-025-00873-1

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