Differential miRNA expression in neural-enriched extracellular vesicles as potential biomarker for frontotemporal dementia and bipolar disorder

Differential miRNA expression in neural-enriched extracellular vesicles as potential biomarker for frontotemporal dementia and bipolar disorder

Behavioral variant of Frontotemporal Dementia (bvFTD) and Bipolar Disorder (BD) share overlapping symptoms, complicating diagnosis. BvFTD, especially linked to C9orf72 expansions, often mimics BD, highlighting the need for reliable biomarkers. This study aimed to differentiate bvFTD from BD using mi...

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Main Authors: Maria Serpente, Giuseppe Delvecchio, Chiara Fenoglio, Lorena Di Consoli, Giulia Giudici, Vittoria Borracci, Emanuela Rotondo, Marina Arcaro, Luca Sacchi, Manuela Pintus, Laura Ghezzi, Adele Ferro, Cecilia Prunas, Antonio Callari, Elisa Scola, Fabio M. Triulzi, Andrea Arighi, Paolo Brambilla, Daniela Galimberti
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Neurobiology of Disease
Subjects:
Neural-enriched extracellular vesicles
miRNAs
Frontotemporal dementia
Bipolar disorder
Biomarkers
Online Access:http://www.sciencedirect.com/science/article/pii/S096999612500083X
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http://www.sciencedirect.com/science/article/pii/S096999612500083X

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