Ursolic acid suppresses triple-negative breast cancer progression through mediating FABP4/PPARG pathway

Ursolic acid suppresses triple-negative breast cancer progression through mediating FABP4/PPARG pathway

Abstract Background Triple-negative breast cancer (TNBC) remains the deadliest subtype of breast cancer owing to high metastatic potential and poor prognosis. Herein, we examined the antitumor effects of ursolic acid (UA), a pentacyclic triterpene compound, against TNBC and the underlying mechanisms...

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Bibliographic Details
Main Authors: Ying Deng, Junyi Wu, Di Pan, Wan Su, Songpo Wang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:European Journal of Medical Research
Subjects:
Ursolic acid
Triple-negative breast cancer
FABP4/PPARG pathway
Proliferation
Migration
Online Access:https://doi.org/10.1186/s40001-025-02794-y
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https://doi.org/10.1186/s40001-025-02794-y

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