Expression Analysis of Heavy-Chain-Only Antibodies in Cloudy Catshark and Japanese Bullhead Shark

Expression Analysis of Heavy-Chain-Only Antibodies in Cloudy Catshark and Japanese Bullhead Shark

Heavy chain-only antibodies in sharks are called immunoglobulin new antigen receptors (IgNAR), consisting of one variable region (VNAR) and five constant regions (C1-C5). The variable region of IgNAR can be expressed as a monomer composed of a single domain, which has antigen specificity and is thus...

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Bibliographic Details
Main Authors: Reo Uemura, Susumu Tanimura, Nao Yamaguchi, Ryuichi Kuroiwa, Gabriel Takashi Andrés Tsutsumi, Toshiaki Fujikawa, Kiyoshi Soyano, Kohsuke Takeda, Yoshimasa Tanaka
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Marine Drugs
Subjects:
cloudy catshark
heavy-chain-only antibody
immunoglobulin new antigen receptor
Japanese bullhead shark
VNAR-domain antibody
Online Access:https://www.mdpi.com/1660-3397/23/1/28
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